IF007
Interferon-α A Protein, Recombinant human
Purified Recombinant Human Interferon Alpha A (Hu-IFN-alphaA & Hu-IFN-alpha2a).
Synonym(s):
Interferon alpha-2
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75
Recommended Products
biological source
human
Quality Level
recombinant
expressed in E. coli
Assay
95%
form
liquid
manufacturer/tradename
Chemicon®
technique(s)
cell culture | mammalian: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Related Categories
General description
Product Source: cDNA obtained from human leukocyte mRNA expressed in E. coli.
Purified Recombinant Human Interferon Alpha A (Hu-IFN-alphaA; Hu-IFN-alpha2a). Human Gene: IFNA2
Unit Definition
Specific Activity: The units are determined with respect to the international reference standard for human interferon alpha A (Hu-IFN-alphaA) provided by the National Institutes of Health.Unit of activity measured on bovine MDBK cells challenged with vesicular stomatitis virus (VSV).
Physical form
Frozen, in PBS containing 0.1% bovine serum albumin (BSA).
Storage and Stability
After receipt, this product should be kept at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Dilute only in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Analysis Note
Specific Activity: Determined by assaying inhibition of virus-induced cytopathic effect.In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Manabu Taura et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(20), e2011665119-e2011665119 (2022-05-14)
APOBEC3A (A3A) is a cytidine deaminase that inactivates a variety of viruses through introduction of lethal mutations to the viral genome. Additionally, A3A can suppress HIV-1 transcription in a deaminase-independent manner by binding to the long terminal repeat of proviral
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