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850144P

Avanti

18:0-20:4 PI

Avanti Research™ - A Croda Brand

Synonym(s):

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); SAPI; PI(18:0/20:4(5Z,8Z,11Z,14Z)); 110661

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About This Item

Empirical Formula (Hill Notation):
C47H86NO13P
CAS Number:
1331751-28-0
Molecular Weight:
904.16
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol (ammonium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850144P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850144P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP(OC[C@H](OC([C19H31])=O)COC(CCCCCCCCCCCCCCCCC)=O)([O-])=O.[NH4+]

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Application

18:0-20:4 PI or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol (ammonium salt) has been used:
  • as a negative control to evaluate the specificity of the interaction between cholesterol sulfate and receptor Mincle by surface plasmon resonance (SPR) experiment
  • as a test lipid in liposomes harboring candidate triggering receptor expressed on myeloid cells 2 (TREM2) ligands, to assess TREM2 stimulation
  • as a reference in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis to identify PI(18:0/20:4) in cancer tissue-originated spheroids (CTOSs) extraction

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850144P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850144P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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