840506C

18:0-22:6 PG

1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

• Synonym(s): 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); 110655
• Empirical Formula (Hill Notation): C₄₆H₇₈O₁₀PNa
• CAS Number: 474943-27-6
• Molecular Weight: 845.07
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (840506C-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 840506C
• concentration: 10 mg/mL (840506C-25mg)
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C46H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-20-21-22-24-26-28-30-32-34-36-38-46(50)56-44(42-55-57(51,52)54-40-43(48)39-47)41-53-45(49)37-35-33-31-29-27-25-23-18-16-14-12-10-8-6-4-2;/h5,7,11,13,17,19,21-22,26,28,32,34,43-44,47-48H,3-4,6,8-10,12,14-16,18,20,23-25,27,29-31,33,35-42H2,1-2H3,(H,51,52);/q;+1/p-1/b7-5-,13-11-,19-17-,22-21-,28-26-,34-32-;/t43?,44-;/m1./s1
• InChI key: MZXILCJOOQSOIZ-DTRIVZRESA-M

Description

General description

18:0-22:6 PG or 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1′-rac-glycerol) is a sodium salt of glycerophospholipid, with substitution of stearic acid, docosahexaenic acid and phospho-rac-(1-glycerol) at the sn-1, sn-2 and sn-3 positions respectively, in the glycerol backbone.

Application

18:0-22:6 PG or 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt) has been used as a standard in bilayer vesicles for the systematic analysis of different oxidized phospholipid (Ox-PL) patterns by oxidation of PL vesicles using a Cu²⁺ solution. It has also been used in liposomes, to serve as an acidic phospholipid control and to determine the lipid-binding properties of the Praja-1 protein and also its E3 ubiquitin-protein ligase action.

Packaging

5 mL Clear Glass Sealed Ampule (840506C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• WGK: WGK 3