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B84904

Sigma-Aldrich

2,3-Butanediol

98%

Synonym(s):

2,3-Butylene glycol

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About This Item

Linear Formula:
CH3CH(OH)CH(OH)CH3
CAS Number:
513-85-9
Molecular Weight:
90.12
Beilstein:
969165
EC Number:
208-173-6
MDL number:
MFCD00004523
UNSPSC Code:
12352100
PubChem Substance ID:
24892073
NACRES:
NA.22

Quality Level

200

Assay

98%

form

liquid

refractive index

n20/D 1.433 (lit.)

bp

183-184 °C (lit.)

mp

25 °C (lit.)

density

1.002 g/mL at 20 °C (lit.)

SMILES string

CC(O)C(C)O

InChI

1S/C4H10O2/c1-3(5)4(2)6/h3-6H,1-2H3

InChI key

OWBTYPJTUOEWEK-UHFFFAOYSA-N

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General description

2,3-Butanediol (2,3-BDO) is used as precursor in the synthesis of cyclic carbonates and methyl ethyl ketone.

Application

  • CRISPR/Cas9 in Pichia pastoris: 2,3-Butanediol (BDO) is used in the construction of P. pastoris cell factories as a representative example to demonstrate the procedures for integrating multiple heterologous genes using the CRISPR-based multiplex genome integration toolkit (Gao et al., 2024).
  • Antifungal activity in sorghum: 2,3-butanediol, a metabolite of A. oryzae YRA3, can induce the production of root exudates which modulate the growth of the rhizospheric fungi and bacteria (Rashad et al., 2023).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

185.0 °F - closed cup

Flash Point(C)

85 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Natsuo Ueda et al.
Neuropharmacology, 48(8), 1079-1085 (2005-05-25)
It is widely accepted that fatty acid amide hydrolase (FAAH) plays a central role in the hydrolysis of anandamide. However, we found a second N-acylethanolamine hydrolase in animal tissues which hydrolyzed anandamide at acidic pH. This "acid amidase" was first
Xiao-Jun Ji et al.
Biotechnology advances, 29(3), 351-364 (2011-01-29)
2,3-butanediol is a promising bulk chemical due to its extensive industry applications. The state-of-the-art nature of microbial 2,3-butanediol production is reviewed in this paper. Various strategies for efficient and economical microbial 2,3-butanediol production, including strain improvement, substrate alternation, and process
E Celińska et al.
Biotechnology advances, 27(6), 715-725 (2009-05-16)
Biotechnological production of 2,3-butanediol (hereafter referred to as 2,3-BD) from wastes and excessive biomass is a promising and attractive alternative for traditional chemical synthesis. In the face of scarcity of fossil fuel supplies the bio-based process is receiving a significant
Frank Plaisant et al.
Free radical biology & medicine, 34(7), 862-872 (2003-03-26)
The pathophysiology of brain lesions associated with cerebral palsy is multifactorial and likely involves excess release of glutamate and excess production of free radicals, among other factors. Theoretically, antioxidants could limit the severity of these brain lesions. Peroxiredoxins are a
Patricia Hermand et al.
The Journal of biological chemistry, 278(7), 4892-4898 (2002-12-13)
ICAM-4 (LW blood group glycoprotein) is an erythroid-specific membrane component that belongs to the family of intercellular adhesion molecules and interacts in vitro with different members of the integrin family, suggesting a potential role in adhesion or cell interaction events
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Protocols

GC Analysis of Glycols on Nukol™

99%; Glycerol, ≥99.5%; Tetraethylene glycol, 99%

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