B4856
Diphenylmethanol
99%
Synonym(s):
Benzhydrol, Benzhydryl alcohol, Diphenyl carbinol
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About This Item
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Assay
99%
form
powder
bp
297-298 °C (lit.)
mp
65-67 °C (lit.)
SMILES string
OC(c1ccccc1)c2ccccc2
InChI
1S/C13H12O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13-14H
InChI key
QILSFLSDHQAZET-UHFFFAOYSA-N
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Application
Diphenylmethanol is used in the carbene-catalyzed dynamic kinetic resolution of α,α-disubstituted carboxylic esters. It can also be used in the chiral resolution of free-base and Ni(II) porphyrinoid complexes.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Helimeric porphyrinoids: stereostructure and chiral resolution of meso-tetraarylmorpholinochlorins.
Journal of the American Chemical Society, 133(22), 8740-8752 (2011)
Bioorganic & medicinal chemistry, 20(9), 3072-3093 (2012-04-03)
In the present article, we have reported the design, synthesis, and identification of highly potent benzhydrol derivatives as squalene synthase inhibitors (compound 1). Unfortunately, the in vivo efficacies of the compounds were not enough for acquiring the clinical candidate. We
Bioorganic & medicinal chemistry, 19(16), 4704-4709 (2011-07-27)
A series of (±)-benzhydrol derivatives featuring the essential sulfonamide group at the para position on the C-ring were synthesized and evaluated for the potential anti-HIV activity in C8166 cells. Most of these analogues demonstrated low concentration inhibitory activity with EC(50)
Carbene-Catalyzed Dynamic Kinetic Resolution of Carboxylic Esters.
Journal of the American Chemical Society, 138(23), 7212-7215 (2016)
Alkylation of alcohols for gas chromatographic analysis by a phase transfer catalysis technique. Evaluation of benzhydrol benzylation in a one-phase system.
Acta pharmaceutica Suecica, 16(4), 247-262 (1979-01-01)
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