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Quality Level
Assay
97%
mp
65-69 °C (lit.)
functional group
amine
carboxylic acid
SMILES string
CC(O)=O.CC(C)(C)NO
InChI
1S/C4H11NO.C2H4O2/c1-4(2,3)5-6;1-2(3)4/h5-6H,1-3H3;1H3,(H,3,4)
InChI key
QGYZLVSWEOXOFT-UHFFFAOYSA-N
General description
N-(tert-Butyl)hydroxylamine acetate (NtBuHA acetate) is a derivative of hydroxylamine that shows thioesterase-mimetic and antioxidant characteristics.
Application
N-(tert-Butyl)hydroxylamine acetate has been used in a study to understand its effect on CD (cathepsin D) activity.
It may be used in the preparation of:
It may be used in the preparation of:
- (Z)-α-5-bromo-N-tert-butyl-2-methoxyphenylnitrone
- ONO-type pincer ligand
- hydroxyphenyl nitrones
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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(Z)-α-5-Bromo-N-tert-butyl-2-methoxyphenylnitrone.
Acta Crystallographica Section E, Structure Reports Online, 63(10), 3943-3943 (2007)
Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.
European Journal of Medicinal Chemistry, 58, 44-49 (2012)
Human molecular genetics, 24(19), 5416-5432 (2015-07-15)
Neurodegeneration is a devastating manifestation in the majority of >50 lysosomal storage disorders (LSDs). Neuronal ceroid lipofuscinoses (NCLs) are the most common childhood neurodegenerative LSDs. Mutations in 13 different genes (called CLNs) underlie various types of NCLs, of which the
Ruthenium ONO-Type Pincer Complex: Synthesis, Structural Characterization, and Catalysis.
Advanced Synthesis & Catalysis, 352(10), 1779-1783 (2010)
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