407038
Poly(ethylene glycol) bis(carboxymethyl) ether
average MN 600, cross-linking reagent amine reactive, carboxylic acid
Synonym(s):
Polyethylene glycol, Polyethylene glycol 600 diacid, Polyglycol 600 diacid
About This Item
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product name
Poly(ethylene glycol) bis(carboxymethyl) ether, average Mn 600
form
viscous liquid
mol wt
average Mn 600
reaction suitability
reagent type: cross-linking reagent
reactivity: amine reactive
density
1.191 g/mL at 25 °C
Ω-end
carboxylic acid
α-end
carboxylic acid
polymer architecture
shape: linear
functionality: homobifunctional
SMILES string
OCCO.OCC(O)=O
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
572.0 °F - closed cup
Flash Point(C)
300 °C - closed cup
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Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.
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