391956
Dimethylamine solution
2.0 M in THF
Synonym(s):
N,N-Dimethylamine
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About This Item
Linear Formula:
(CH3)2NH
CAS Number:
Molecular Weight:
45.08
Beilstein:
605257
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
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form
liquid
Quality Level
concentration
1.90-2.20 M (by NaOH, titration)
2.0 M in THF
bp
~60 °C
density
0.85 g/mL at 25 °C
functional group
amine
SMILES string
CNC
InChI
1S/C2H7N/c1-3-2/h3H,1-2H3
InChI key
ROSDSFDQCJNGOL-UHFFFAOYSA-N
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Application
Dimethylamine solution (2M in THF) has been used in the synthesis of 2-dimethylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (bk-MDDMA) , a β-keto derivative of 3,4-methylenedioxyamphetamine (MDA) by reacting with 2-bromo-3′,4′-methylenedioxypropiophenone. It may also be used to synthesize organic intermediates such as dimethyl-(4-nitro-benzyl)-amine, dimethyl-(4-methyl-benzyl)-amine and 4-dimethylamino-but-2-enoic acid [4-(3,4-dichloro-6-fluoro-phenylamino)-quinazolin-6-yl]-amide.
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Central nervous system, Respiratory system
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
-32.8 °F - closed cup
Flash Point(C)
-36 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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