358754

1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine, polymer-bound

200-400 mesh, extent of labeling: 2.6 mmol/g loading, 2 % cross-linked with divinylbenzene

• Synonym(s): 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine bound to polystyrene, 1,5,7-Triazabicyclo[4.4.0]dec-5-ene–polystyrene crosslinked with 2% DVB, ‘7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene’ on polystyrene
• UNSPSC Code: 12352128
• NACRES: NA.22

Properties

• crosslinking: 2 % cross-linked with divinylbenzene
• reaction suitability: reaction type: solution phase peptide synthesis; reactivity: proton reactive
• extent of labeling: 2.6 mmol/g loading
• particle size: 200-400 mesh

Description

Features and Benefits

This versatile polymer-bound base has been used as a reusable basic catalyst foe regioselective acylations; as both a base for the deprotonation of phenols and as a scavenger of excess phenil in the synthesis of aryl ethers from phenols; in the addition of dialkyl phosphites to a variety of carbonyl compounds, as well as, serving as a catalyst in the nitroaldol (Henry) reaction; and as a scavenger of activated ester electophiles.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves