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357898

Sigma-Aldrich

Serinol

98%

Synonym(s):

2-Amino-1,3-propanediol

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About This Item

Linear Formula:
HOCH2CH(NH2)CH2OH
CAS Number:
Molecular Weight:
91.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

bp

277 °C (lit.)

mp

52-55 °C (lit.)

SMILES string

NC(CO)CO

InChI

1S/C3H9NO2/c4-3(1-5)2-6/h3,5-6H,1-2,4H2

InChI key

KJJPLEZQSCZCKE-UHFFFAOYSA-N

General description

Serinol activates toxin production in the attenuated cultures of Helminthosporium sacchari. Preparation of polyesters derived from serinol is reported.

Application

Serinol may be used to prepare the artificial nucleic acids. It may be used in the synthesis of N-acylated serinol and C16-serinol affinity gel.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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E Bieberich et al.
The Journal of biological chemistry, 275(1), 177-181 (2000-01-05)
A novel structural analog of ceramide was synthesized by N-acylation of serinol (2-amino-1,3-propanediol) and studied for its effects on glycolipid biosynthesis and cell differentiation of neuroblastoma cells. Incubation with N-palmitoylated serinol (C16-serinol) increased the concentration of endogenous ceramide by 50-80%
F Pinkerton et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(11), 4007-4011 (1976-11-01)
Successive transfer in synthetic medium of spores and mycelial fragments from original toxin-producing cultures of Helminthosporium sacchari results in attenuated cultures which do not produce the host-specific toxin helminthosporoside. When attenuated cultures are grown on material obtained from the water
Hiroyuki Asanuma et al.
Chemical record (New York, N.Y.), 14(6), 1055-1069 (2014-08-30)
In this account, we demonstrate a new methodology for the de novo design of functional oligonucleotides with the acyclic scaffolds threoninol and serinol. Four functional motifs-wedge, interstrand-wedge, dimer, and cluster-have been prepared from natural DNA or RNA and functional base
Daniele Locatelli et al.
Nanomaterials (Basel, Switzerland), 10(6) (2020-06-21)
The solubility parameters of multiwalled carbon nanotubes (CNTs) was tuned via their chemical modification with pyrrole compounds (PyCs), by means of a simple and sustainable methodology. PyCs were synthesized with high atom efficiency through the Paal-Knorr reaction of primary amines
B N Trawick et al.
Bioconjugate chemistry, 12(6), 900-905 (2001-11-22)
The syntheses and RNA cleavage efficiencies of a new series of oligonucleotide conjugates of Cu(II)-serinol-terpyridine and 1,3-propanediol are reported. These reagents, termed ribozyme mimics, were designed such that they would yield multiple unpaired RNA residues directly opposite the site of

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