149497

Methyl diphenylphosphinite

97%

• Synonym(s): Diphenylmethoxyphosphine, Methoxydiphenylphosphine, NSC 171167
• Linear Formula: (C₆H₅)₂POCH₃
• CAS Number: 4020-99-9
• Molecular Weight: 216.22
• EC Number: 223-683-9
• MDL number: MFCD00048025
• UNSPSC Code: 12352108
• PubChem Substance ID: 24848958
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• refractive index: n20/D 1.604 (lit.)
• bp: 149 °C/6 mmHg (lit.)
• density: 1.078 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: COP(c1ccccc1)c2ccccc2
• InChI: 1S/C13H13OP/c1-14-15(12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11H,1H3
• InChI key: OAADXJFIBNEPLY-UHFFFAOYSA-N

Description

Application

Ased as:

• Catalyst for hydroformylative desymmetrization of bisalkenyl carbinols and bishomoallylic carbinols
• Ligand in rhodium-catalyzed hydroformylation of bishomoallylic alcohols
• Calatyst in preparation of γ-lactones via branched-regioselective hydroformylation reactions
• Ligand for nickel-catalyzed hydrocyanation reactions
• Catalyst in annulation reactions

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): >235.4 °F - closed cup
• Flash Point(C): > 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves