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Visiprep SPE Vacuum Manifold, PTFE Free

new

standard, 24-port model

Synonym(s):

24-port SPE Vacuum Manifold for cartidges

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About This Item

UNSPSC Code:
41121800
NACRES:
NB.21

material

UHMW PE frit
polypropylene tube

Agency

suitable for DIN 38407-42
suitable for EPA 1633
suitable for EPA 533
suitable for EPA 537.1
suitable for EPA ACB B21-02
suitable for EPA ACB B23-05b
suitable for EPA OTM-45
suitable for GB 31604.35-2016
suitable for ISO 21675 2019
suitable for ISO 25101
suitable for ISO/CEN 15968-2010

reg. compliance

suitable for FDA C-010.02

product line

Visiprep

technique(s)

solid phase extraction (SPE): suitable

suitability

suitable for (for PFAS Testing)

application(s)

environmental
food and beverages

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General description

Visiprep Solid Phase Extraction Vacuum Manifolds andaccessories automate the preparation and cleanup of laboratory liquid samplesby solid phase extraction. Used with a vacuum pump, a Visiprep™ manifold canextract up to 12 or up to 24 samples simultaneously, significantly increasingsample throughput while decreasing sample preparation hands-on time, relativeto liquid-liquid extraction methods. Visiprep vacuum manifolds feature avacuum bleed valve and a stand-alone coverto provide you with precise flow control and safe, easy use.With our flow control valves you can precisely manipulate flow through eachtube by rotating the individual screw-valves built into the cover. Our recentlyoptimized standard manifolds are suitable for SPE methods in the PFAS testingarea. All crucial components that contain PFAS (e.g. PTFE) are substituted byPFAS free alternatives like e.g ultra-high molecular weight Polyethylene (UHMWPE) or stainless steel (needle guides). These ensure low PFAS backgroundcontamination during the SPE process. The glass basin will not dissolve, fog,or discolor when exposed to powerful solvents. The manifold rack accommodatesautosampler or small scintillation vials, 10 mm or 16 mm test tubes, or 1, 2, 5or 10 mL volumetric flasks. An optional plate fits up to ten 20 mLscintillation vials in the 12-port model. The vacuum bleed valve improves control of the vacuum level andensures more secure closure of the valve. This screw-type valve is fitted withan ultra-high molecular weight polyethylene cone shaped seal (now PTFE-free).Tightening the screw ensures a complete seal with no leakage at the valve.Loosening the screw breaks the seal, allowing immediate vacuum release to stopextractions or to lift the manifold cover. Four 2" legs enable you tostand the cover on a work surface with the SPE tubes maintaining their uprightpositions. This prevents solvent guides from resting on the work surface andbecoming damaged or contaminated. Drying attachment on themanifold is sold separately, it installs in minutes and can be used with anyinert gas. The drying attachment also is useful for concentrating recoveredsamples. Gas flow to each tube can be independently adjusted.

Application


  • pH-sensitive pullulan-doxorubicin nanoparticles loaded with 1,1,2-trichlorotrifluoroethane as a novel synergist for high intensity focused ultrasound mediated tumor ablation: This innovative approach employs 1,1,2-Trichlorotrifluoroethane in nanoparticle formulations to enhance the efficacy of tumor treatments through high intensity focused ultrasound, showcasing its potential in pharmaceutical applications (Li et al., 2019).

  • Chemical analysis and risk assessment of diethyl phthalate in alcoholic beverages with special regard to unrecorded alcohol: Although primarily focused on diethyl phthalate, this study highlights the broader scope of solvent safety in pharmaceuticals, suggesting indirect implications for handling and safety assessments of solvents like 1,1,2-Trichlorotrifluoroethane (Leitz et al., 2009).

  • Quantitative determination of n-propane, iso-butane, and n-butane by headspace GC-MS in intoxications by inhalation of lighter fluid: This research demonstrates the use of advanced analytical techniques for volatile substances, which could be analogous to methodologies applied in studying environmental and safety aspects of 1,1,2-Trichlorotrifluoroethane in industrial settings (Bouche et al., 2002).

Features and Benefits

  • Patented screw-type valves within each SPE port for precise flowcontrol
  • Glass basin will not dissolve, fog, or discolor when exposed tosolvents
  • Legs on cover allow user to easily rest cover on work surface whenremoved from the manifold
  • Screw-type solvent-resistant vacuum bleed gauge and valve offerbetter sealing and vacuum control. Valve takes 1/4″ vacuumtubing.
  • PP collection vessel rack accommodates autosampler vials; smallscintillation vials (22.75 mm O.D. recommended); 10 and 16 mm test tubes; and 1, 2, 5, and 10 mL volumetric flasks. An optional plate for 20 mL scintillationvials is available for 12-port models.

Legal Information

Visiprep is a trademark of Sigma-Aldrich Co. LLC

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Cheng Zhang et al.
Cell, 175(1), 212-223 (2018-09-23)
CRISPR-Cas endonucleases directed against foreign nucleic acids mediate prokaryotic adaptive immunity and have been tailored for broad genetic engineering applications. Type VI-D CRISPR systems contain the smallest known family of single effector Cas enzymes, and their signature Cas13d ribonuclease employs

Protocols

To optimize hydrolysis using β-glucuronidase, factors such as incubation time, temperature, hydrolysis pH, enzyme source, and enzyme concentration must be evaluated for each glucuronide metabolite to be analyzed.

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