SRP5310
c-KIT (Y823D), active, GST tagged human
PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
CD119, PBT, SCFR
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About This Item
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
product line
PRECISIO®
Assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
0.8-1.2 nmol/min·mg
mol wt
~73 kDa
technique(s)
cell culture | stem cell: suitable
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KIT(3815)
General description
c-KIT (Y823D) encodes the ligand-binding chain (alpha) of the gamma interferon receptor which is a heterodimer of IFNGR1 and IFNGR2. c-KIT (Y823D) is a regulator of hematopoietic stem cells during homeostasis and under conditions of infectious stress. A genetic variation in c-KIT (Y823D) is associated with susceptibility to Helicobacter pylori infection. In addition, defects in c-KIT (Y823D) are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. c-KIT (Y823D is also associated with the clinical outcome of HBV infection in Chinese adults.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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