SRP0387

EZH2 /EED/SUZ12/RbAp48/AEBP2 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥56% (SDS-PAGE)

• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in baculovirus infected Sf9 cells
• Assay: ≥56% (SDS-PAGE)
• form: aqueous solution
• mol wt: 87 kDa (EZH2)
• packaging: pkg of 20 μg
• NCBI accession no.: NM_003797 (EED); NM_004456 (EZH2); NM_005610 (RbAP48); NM_015355 (SUZ12); NM_153207 (AEBP2)
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... AEBP2(121536) , EED(8726) , EZH2(2146) , RBBP4(5928) , SUZ12(23512)

Description

General description

Mutant version of EZH2 5- member complex with a Tyr-to-Asn mutation on amino acids 646 of the EZH2 protein. Complex of human EZH2 (GenBank Accession No. NM_004456), amino acids 2-end (Y646N*) with N-terminal His-tag, MW= 86 kDa, human EED (GenBank Accession No. NM_003797) (amino acids 2-end) with N-terminal Flag-tag, MW= 51 kDa, human SUZ12 (GenBank Accession No. NM_015355) (amino acids 2-end) with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (GenBank Accession No. NM_153207) (amino acids 2-end) with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (GenBank Accession No. NM_005610) (a-a 2- end) with N-terminal His-tag, MW = 48 kDa, co-expressed in Baculovirus expression system. *This mutation is often cited as Y641N in variant 3 GenBank Accession No. NM_001203247).

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable