SAB5702111

Anti-TSC2 Antibody, clone 7X2C6, Rabbit Monoclonal

• Synonym(s): LAM,PPP1R160,TSC4,TSC2,Tuberin,tuberin
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 7X2C6, monoclonal
• form: liquid
• mol wt: 200 kDa
• species reactivity: human
• concentration: 0.52 mg/mL
• technique(s): immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: AKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
• UniProt accession no.: P49815
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TSC2(7249)

Description

General description

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1700-1807 of human Tuberin (P49815).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB,IP

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1