SAB5701888

Anti-Phospho-p70 S6 Kinase 1-Thr421 antibody produced in rabbit

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human
• concentration: 0.72 mg/mL
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P23443
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr421)
• Gene Information: human ... RPS6KB1(6198)

Description

General description

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Immunogen

A phospho specific peptide corresponding to residues surrounding Thr421 of human RPS6KB1.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable