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G8148

Sigma-Aldrich

Gly-Arg-p-nitroanilide dihydrochloride

unokinase and plasmin substrate

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About This Item

Empirical Formula (Hill Notation):
C14H21N7O4 · 2HCl
CAS Number:
125455-61-0
Molecular Weight:
424.28
MDL number:
MFCD00083360
UNSPSC Code:
12352204
PubChem Substance ID:
24895332
NACRES:
NA.32

Assay

≥98% (TLC)

form

powder

solubility

methanol: 20 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl.NCC(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc(cc1)N(=O)=O

InChI

1S/C14H21N7O4.ClH/c15-8-12(22)20-11(2-1-7-18-14(16)17)13(23)19-9-3-5-10(6-4-9)21(24)25;/h3-6,11H,1-2,7-8,15H2,(H,19,23)(H,20,22)(H4,16,17,18);1H

InChI key

MGFMNXNZZCRYAQ-UHFFFAOYSA-N

Substrates

Substrate for plasmin and urokinase

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB6961
BCBZ4822
BCBP0113
BCBN8343V
BCBN8343

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Flourogenic peptide amide substrates for the estimation of plasminogen activators and plasmin.
W Nieuwenhuizen et al.
Analytical biochemistry, 83(1), 143-148 (1977-11-01)
Ning Luan et al.
Thrombosis and haemostasis, 117(6), 1031-1039 (2017-03-10)
The repugnatorial glands of millipedes release various defensive chemical secretions. Although varieties of such defensive secretions have been studied, none of them is protein or peptide. Herein, a novel factor Xa (FXa) inhibitor named joannsin was identified and characterised from repugnatorial glands
Thiago Pajeú Nascimento et al.
Bioprocess and biosystems engineering, 40(8), 1209-1219 (2017-05-14)
Fibrinolytic proteases are enzymes that degrade fibrin. They provide a promising alternative to existing drugs for thrombolytic therapy. A protease isolated from the filamentous fungus Mucor subtilissimus UCP 1262 was purified in three steps by ammonium sulfate fractionation, ion exchange

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