D9565

β-Defensin 1 human

≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

• MDL number: MFCD01865661
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• recombinant: expressed in E. coli
• Quality Level: 200
• Assay: ≥98% (HPLC and SDS-PAGE)
• form: lyophilized powder (from 10 mM acetic acid)
• mol wt: estimated mol wt 3.9 kDa
• UniProt accession no.: P60022
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria; fungi; viruses
• Mode of action: cell wall synthesis | interferes
• storage temp.: −20°C
• Gene Information: human ... DEFB1(1672)

Description

Amino Acid Sequence

Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide bridges 5-34, 12-27, and 17-35]

General description

Chemical structure: peptide

Biochem/physiol Actions

A small cationic peptide which demonstrates anti-microbial activity. Originally isolated from human plasma, this substance is constitutively expressed in mucosal membrane epithelium.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves