B0936

BRL 50481

≥98% (HPLC), solid

• Synonym(s): 5-Nitro-2,N,N-trimethylbenzenesulfonamide
• Empirical Formula (Hill Notation): C₉H₁₂N₂O₄S
• CAS Number: 433695-36-4
• Molecular Weight: 244.27
• MDL number: MFCD03039912
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277757
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• color: white to off-white
• solubility: DMSO: >10 mg/mL; H₂O: insoluble
• originator: GlaxoSmithKline
• storage temp.: 2-8°C
• SMILES string: CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
• InChI: 1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3
• InChI key: IFIUFCJFLGCQPH-UHFFFAOYSA-N
• Gene Information: human ... PDE7A(5150) , PDE7B(27115)

Description

Biochem/physiol Actions

BRL 50481 is a potent and selective PDE7 inhibitor (IC50 = 260 nM).

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves