124737
Glycolic acid
ReagentPlus®, 99%
Synonym(s):
Hydroxyacetic acid
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All Photos(3)
About This Item
Linear Formula:
HOCH2COOH
CAS Number:
Molecular Weight:
76.05
Beilstein:
1209322
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39021303
PubChem Substance ID:
NACRES:
NA.21
Recommended Products
Quality Level
product line
ReagentPlus®
Assay
99%
form
solid
mp
75-80 °C (lit.)
solubility
H2O: 50 mg/mL, clear, colorless
functional group
carboxylic acid
hydroxyl
SMILES string
OCC(O)=O
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI key
AEMRFAOFKBGASW-UHFFFAOYSA-N
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General description
Glycolic acid (Hydroxyacetic acid) is an α-hydroxy acid. Glycolic acid solutions having concentration of 70% and pH range of 0.08 to 2.75 are widely employed as superficial chemical peeling agents. Various oligomers or polymers of lactic and/or glycolic acid (low molecular weight) have been prepared. Glycolic acid can be determined via plant tissue coupled flow injection chemiluminescence biosensors, which can be used both as a plant-tissue based biosensor and chemiluminescence flow sensor.
Application
Glycolic acid (Hydroxyacetic acid) has been used in the preparation of PLGA-PEG-PLGA copolymer (PLGA = poly(lactic/glycolic, PEG = polyethylene glycol).
Other Notes
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 1
Flash Point(F)
>572.0 °F - (decomposition)
Flash Point(C)
> 300 °C - (decomposition)
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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"A novel renewable plant tissue-based electrochemiluminescent biosensor for glycolic acid"
Zhu L, et al.
Sensors and Actuators B, Chemical, 98(2), 115-121 (2004)
Sima Shahabi et al.
TheScientificWorldJournal, 2014, 420616-420616 (2015-01-13)
Gamma irradiation is able to affect various structural and biological properties of biomaterials In this study, a composite of Hap/PLGA-PEG and their ingredients were submitted to gamma irradiation doses of 25 and 50 KGy. Various properties such as molecular weight (GPC)
?Plant Tissue-Based Chemiluminescence Flow Biosensor for Glycolic Acid?
Li B, et al.
Analytical Chemistry, 73(6), 1203-1206 (2001)
N Wang et al.
Journal of biomaterials science. Polymer edition, 8(12), 905-917 (1997-01-01)
A series of oligomers or low molecular weight polymers of lactic and/or glycolic acid has been synthesized with different molar ratios of lactic to glycolic acid. These oligomers have been characterized with respect to oligomer composition, molecular weight, intrinsic viscosity
F F Becker et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 22(5), 463-465 (1996-05-01)
Seventy percent glycolic acid solutions are being commonly used as superficial chemical peeling agents. The pH of these solutions ranges from 0.08 to 2.75. The histologic effects of these various pH solutions on human skin have not been studied. The
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