565191
Anti-Serum Amyloid P Component Rabbit pAb
liquid, Calbiochem®
Synonym(s):
Anti-SAP
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.43
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
should not react with
mouse
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes serum amyloid P component.
Recognizes serum amyloid P component.Antibody Target Gene Symbol: APCS Target Synonym: MGC88159, PTX2, SAP, Serum amyloid p-component Entrez Gene Name: amyloid P component, serum Hu Entrez ID: 325 Mu Entrez ID: 20219 Rat Entrez ID: 29339
This Anti-Serum Amyloid P Component Rabbit pAb is validated for use in ELISA, Immunoelectrophoresis, IF, IHC, Ouchterlony, Radial Immunodiffusion for the detection of Serum Amyloid P Component.
Immunogen
Human
purified human SAP component
Application
ELISA (see comments)
Immunoelectrophoresis (see comments)
Immunofluorescence (1:20-1:50)
Immunohistochemistry (1:200)
Ouchterlony (see comments)
Radial Immunodiffusion (see comments)
Immunoelectrophoresis (see comments)
Immunofluorescence (1:20-1:50)
Immunohistochemistry (1:200)
Ouchterlony (see comments)
Radial Immunodiffusion (see comments)
Warning
Toxicity: Standard Handling (A)
Physical form
Undiluted serum.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Monospecific for serum amyloid P as determined by ouchterlony and immunoelectrophoresis. Immunofluorescence and immunoperoxidase staining of human tissues specifically identifies only those structures known to contain SAP. This antibody has also been reported to work for ELISA and radial immunodiffusion. Variables associated with assay conditions will dictate the optimal working dilution.
Serban, D., and Rordorf-Adam, C. 1986. J. Immunol. Methods90, 159.
Pepys, M.B., et al. 1979. Nature278, 259.
Pepys, M.B., et al. 1979. Nature278, 259.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
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Katrine Pilely et al.
Frontiers in immunology, 8, 1040-1040 (2017-09-14)
Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component
Andrea Doni et al.
Nature communications, 12(1), 3739-3739 (2021-06-20)
Serum amyloid P component (SAP, also known as Pentraxin 2; APCS gene) is a component of the humoral arm of innate immunity involved in resistance to bacterial infection and regulation of tissue remodeling. Here we investigate the role of SAP
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