Skip to Content
Merck
All Photos(1)

Documents

M-083

Supelco

Methylphenidate hydrochloride solution

(Racemic mixture), ampule of 1 mL, 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C14H20ClNO2
CAS Number:
Molecular Weight:
269.77
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

Cl.COC(=O)C(C1CCCCN1)c2ccccc2

InChI

1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H

InChI key

JUMYIBMBTDDLNG-UHFFFAOYSA-N

Gene Information

General description

Methylphenidate is a psychostimulant prescribed for treatment of attention-deficit hyperactivity disorder (ADHD), tachycardia and narcolepsy. This Certified Spiking Solution® is applicable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology and forensic analysis. Methylphenidate is sold under trade names Concerta® and Ritalin®.

Application


  • Methylphenidate HCl solution in ADHD pharmacotherapy studies: Research published in "Molecular Psychiatry" explored the effects of methylphenidate on Drosophila brain at single-cell resolution, highlighting its potential for ADHD treatment repurposing and its impact on neurotransmitter regulation (Qu et al., 2023).

  • CNS stimulant research with high-purity methylphenidate HCl: A case study in "Children (Basel)" detailed the complex relationship between ADHD symptoms and self-induced weight loss in a child, underscoring methylphenidate′s role in managing hyperkinetic disorders and its potential interactions with eating behaviors (Mestermann et al., 2023).

  • Neuropharmacology Methylphenidate in neurotransmitter research: A review in "Molecular Biotechnology" discussed the pharmacological applications of amino acids, using methodologies that could be applied to substances like methylphenidate for enhanced understanding of its interaction with brain chemistry and neurotransmitter functions (Kamaraj and Vuppu, 2023).

  • Liquid methylphenidate for in vitro neuropharmacology studies: An analysis in "Journal of Medical Internet Research" investigated the nonmedical use and adverse effects of methylphenidate, providing insights into its impact during the COVID-19 pandemic and highlighting the importance of monitoring drug usage trends for improved public health strategies (Shin et al., 2023).

  • Dopamine reuptake inhibitor research with methylphenidate solution: A report in "Journal of Analytical Toxicology" detailed a case of fatal intoxication where methylphenidate′s properties as a dopamine reuptake inhibitor were considered in the context of its toxicological profile, emphasizing the need for careful monitoring of its use and effects (Ameline et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Concerta is a registered trademark of ALZA Corporation
Ritalin is a registered trademark of Novartis Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service