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870012C

Avanti

18:1 MPB PE

Avanti Research™ - A Croda Brand 870012C

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C55H88N2O11PNa
CAS Number:
384835-49-8
Molecular Weight:
1007.26
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (870012C-25mg)
pkg of 2 × 4 mL (870012C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870012C

concentration

10 mg/mL (870012C-25mg)
25 mg/mL (870012C-200mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCCC(C=C1)=CC=C1N(C(C=C2)=O)C2=O)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C55H89N2O11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36-54(61)65-46-50(68-55(62)37-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)47-67-69(63,64)66-45-44-56-51(58)35-33-34-48-38-40-49(41-39-48)57-52(59)42-43-53(57)60;/h17-20,38-43,50H,3-16,21-37,44-47H2,1-2H3,(H,56,58)(H,63,64);/q;+1/p-1/b19-17-,20-18-;/t50-;/m1./s1

InChI key

IILKDCDPRGFBSN-VCRVZWGWSA-M

General description

Maleimidophenyl butyramide (MPB) phosphoethanolamine (PE), also known as DPPE-maleimide, contains maleimide, which is a thiol-reactive moiety and a good electrophile. MPB PE is implicated in liposome preparation.

Application

18:1 MPB PE has been used in the preparation of nanoparticles. It has also been used in the preparation of interbilayer-crosslinked multilamellar vesicles (ICMVs).

Packaging

5 mL Clear Glass Sealed Ampule (870012C-200mg)
5 mL Clear Glass Sealed Ampule (870012C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases
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European Journal of Pharmaceutics and Biopharmaceutics, 59(2), 263-272 (2005)
Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
Moon J, et al.
Testing, 10(3), 243-243 (2011)
The
Liposomes as tools in basic research and industry (1994)
Camilla Skyttner et al.
Langmuir : the ACS journal of surfaces and colloids, 34(22), 6529-6537 (2018-05-15)
Membrane-active peptides that enable the triggered release of liposomal cargo are of great interest for the development of liposome-based drug delivery systems but require peptide-lipid membrane interactions that are highly defined and tunable. To this end, we have explored the
Emeka B Okeke et al.
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