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131601C

Avanti

Egg PC (95%)

Avanti Polar Lipids

Synonym(s):

L-α-phosphatidylcholine (95%) (Egg, Chicken)

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

chloroform solution

packaging

pkg of 2 × 20 mL (131601C-1g)

manufacturer/tradename

Avanti Polar Lipids

concentration

25 mg/mL (131601C-1g)

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

General description

Egg L-α-phosphatidylcholine (PC) has palmitic acid (16:0) and oleic acid (18:1) at sn-1 and sn-2 positions, respectively. It constitutes 20% of the total phospholipids in egg.
Egg PC (95%) is a mixture of 16 to 22 carbon atoms long acyl chain containing multiple double bonds. Major portion (98%) of phospholipid contains a single saturated and unsaturated chain.
Egg PC is a further purification of Total Egg Extract. This Natural Lipid is a mixture, and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.

Application

Egg PC (95%) has been used for the reconstitution of nhTMEM16 into liposomes.
Egg PC (95%) is suitable for the preparation of multi-lamellar liposomes.
Egg PC (95%) is suitable for use in the liposome preparation for the reconstitution of lipid-linked oligosaccharide (LLO) flippase protein, Protein glyocyslaion K (PglK).

Biochem/physiol Actions

Egg L-α-phosphatidylcholine (PC) is used in lipid preparation and liposomes for biophysical studies. It serves as a substrate for microbes for trimethylamine N-oxide (TMAO) synthesis. Egg PC is used as a marker to access cardiovascular disease (CVD) risk.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (131601C-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM
Kalienkova V, et al.
eLife, 8, e44364-e44364 (2019)
Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation
Perez C, et al.
Structure, 27(4), 669-678 (2019)
Characterization of interactions of eggPC lipid structures with different biomolecules
Chahar FC, et al.
Chemistry and Physics of Lipids, 210, 60-69 (2018)
Egg phospholipids and cardiovascular health
Blesso C
Nutrients, 7(4), 2731-2747 (2015)
Effects of Cholesterol Concentrations on Egg-phosphatidylcholine-Dihexadecyl-phosphate Liposomes Studied by CW ESR and FT-ESEEM Spectroscopy
Mirosavljevic K and Noethig-Laslo V
Croatica Chemica Acta. Arhiv Za Kemiju, 81(4), 631-636 (2008)

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