938688

ImPy-Dipp-IMes

• Synonym(s): 5-(2,6-diisopropylphenyl)-2-mesitylimidazo[1,5-a]pyridin-2-ium chloride
• Empirical Formula (Hill Notation): C₂₈H₃₃ClN₂
• CAS Number: 2983007-39-0
• Molecular Weight: 433.03
• UNSPSC Code: 12352100

Properties

• form: powder
• Quality Level: 100
• reaction suitability: reaction type: Cross Couplings
• color: white
• SMILES string: CC1=CC(C)=CC(C)=C1[N+]2=CN3C(C4=C(C(C)C)C=CC=C4C(C)C)=CC=CC3=C2.[Cl-]
• InChI: 1S/C28H33N2.ClH/c1-18(2)24-11-9-12-25(19(3)4)27(24)26-13-8-10-23-16-29(17-30(23)26)28-21(6)14-20(5)15-22(28)7;/h8-19H,1-7H3;1H/q+1;/p-1
• InChI key: BQLNHZQDABCIAO-UHFFFAOYSA-M

Description

General description

ImPy-Dipp-IMes is an NHC precursor developed in the Szostak group. The ligand is useful in a range of catalytic transformations, and is particularly well suited to the following: Suzuki-Miyaura cross-coupling of aryl mesylates and tosylates, Suzuki–Miyaura cross-coupling of nitroarenes (Ar–NO₂), Buchwald-Hartwig amination of alkyl sulfoxides.

Application

Suzuki-Miyaura cross-coupling of aryl mesylates and tosylates Suzuki–Miyaura cross-coupling of nitroarenes (Ar–NO₂) or aryl sulfamates Buchwald-Hartwig amination of alkyl sulfoxides or aryl sulfamates.

Features and Benefits

ImPy-Dipp-Imes is an asymmetric NHC ligand precursor. It forms air-and moisture stable complexes with transition metals and is particularly effective in palladium catalyzed cross-coupling reactions.