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390593

Sigma-Aldrich

1-(1-Adamantyl)ethylamine hydrochloride

99%

Synonym(s):

α-Methyltricyclo[3.3.1.13,7]-decane-1-methanamine hydrochloride, Rimantadine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H21N · HCl
CAS Number:
1501-84-4
Molecular Weight:
215.76
MDL number:
MFCD00072023
UNSPSC Code:
12352100
PubChem Substance ID:
24864331
NACRES:
NA.22

Assay

99%

mp

>300 °C (lit.)

SMILES string

Cl.C[C@H](N)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI

1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H/t8?,9-,10+,11-,12-;

InChI key

OZBDFBJXRJWNAV-MZHJCFSPSA-N

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Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Georgina Cirrincione-Dall et al.
Journal of clinical pharmacology, 52(8), 1255-1264 (2011-11-01)
Preclinical data suggest increased antiviral activity and less viral resistance when neuraminidase inhibitors and adamantanes are used in combination to harness the complementary effects of their different mechanisms of action. Healthy volunteers were randomized to 5-day oral treatment with oseltamivir
Antiviral drugs for influenza.
The Medical letter on drugs and therapeutics, 54(1381), 1-3 (2012-01-12)
V G Belolipetskaia et al.
Eksperimental'naia i klinicheskaia farmakologiia, 74(7), 38-40 (2011-09-08)
Comparative pharmacokinetics of anti-influenza drug composition Antigrippin-maximum administered in capsules and a powder for preparing solutions has been studied after single administraton in a group of 18 healthy volunteers. Both preparations [manufactured by the Antiviral Research and Production Corporation (St
George Atiee et al.
Journal of clinical pharmacology, 52(9), 1410-1419 (2011-10-01)
Peramivir, an intravenously administered neuraminidase inhibitor, may be used concomitantly with other influenza antivirals. Two studies were conducted to assess the potential for pharmacokinetic interactions of peramivir when coadministered with oseltamivir or rimantadine. Twenty-one healthy subjects were enrolled in each
Loren B Andreas et al.
Biochemistry, 52(16), 2774-2782 (2013-03-14)
We demonstrate the use of dynamic nuclear polarization (DNP) to elucidate ligand binding to a membrane protein using dipolar recoupling magic angle spinning (MAS) NMR. In particular, we detect drug binding in the proton transporter M2(18-60) from influenza A using
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