292087

1-Chloro-2-propanol

70%

• Synonym(s): Chloropropanol, Propylene chlorohydrin
• Linear Formula: CH₃CH(OH)CH₂Cl+CH₃CHClCH₂OH
• CAS Number: 127-00-4
• Molecular Weight: 94.54
• Beilstein: 773653
• EC Number: 204-819-6
• MDL number: MFCD00004530
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857557
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 70%
• impurities: <25% 2-chloro-1-propanol
• refractive index: n20/D 1.439 (lit.)
• bp: 126-127 °C (lit.)
• density: 1.111 g/mL at 25 °C (lit.)
• functional group: chloro; hydroxyl
• SMILES string: CC(O)CCl
• InChI: 1S/C3H7ClO/c1-3(5)2-4/h3,5H,2H2,1H3
• InChI key: YYTSGNJTASLUOY-UHFFFAOYSA-N

Description

General description

1-Chloro-2-propanol is formed as an intermediate during the degradation of meso-bis-(1-chloro-2-propyl)ether by Rhodococcus sp. strain DTB.

Application

1-Chloro-2-propanol has been used as:

• chemical intermediate for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol
• as α,β-halohydrin standard during the enzymatic synthesis of α,β-halohydrins from gaseous alkenes

Safety Information

• Pictograms: GHS02,GHS06
• Signal Word: Danger
• Hazard Statements: H226,H301 + H331,H315,H319,H335
• Precautionary Statements: P210 - P233 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 125.6 °F - closed cup
• Flash Point(C): 52 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves