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287571

Sigma-Aldrich

Bis(2,2,2-trifluoroethyl) ether

98%

Synonym(s):

2,2,2-Trifluoroethyl ether, Flurothyl

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About This Item

Linear Formula:
(CF3CH2)2O
CAS Number:
333-36-8
Molecular Weight:
182.06
Beilstein:
1811927
MDL number:
MFCD00010604
UNSPSC Code:
12352100
PubChem Substance ID:
24857279
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.300 (lit.)

bp

62-63 °C (lit.)

density

1.404 g/mL at 25 °C (lit.)

SMILES string

FC(F)(F)COCC(F)(F)F

InChI

1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2

InChI key

KGPPDNUWZNWPSI-UHFFFAOYSA-N

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Application

Bis(2,2,2-trifluoroethyl) ether was used to diminish self-discharge of Li-S cells having both low- and high-sulfur-loading sulfur cathodes.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

33.8 °F - closed cup

Flash Point(C)

1 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Omar I Khan et al.
Neurobiology of disease, 39(3), 362-371 (2010-05-11)
Frequent interictal spikes are a common finding in the electroencephalograms of children with epileptic encephalopathies. While it is well recognized that interictal spikes are a biological marker of seizures and can lead to transitory cognitive impairment, whether interictal spikes can
Megan Leigh Lewis et al.
Epilepsia, 59(7), 1316-1326 (2018-06-03)
In different cohorts, 5%-30% of individuals with autism spectrum disorder (ASD) also have epilepsy. The high co-occurrence of these disorders suggests that a common mechanistic link may exist. The underlying pathophysiology of this comorbidity remains unknown. To investigate the mechanism(s)
Stacey B B Dutton et al.
Epilepsia, 52(11), 2050-2056 (2011-08-02)
We evaluated the ability of the ketogenic diet (KD) to improve thresholds to flurothyl-induced seizures in two mouse lines with Scn1a mutations: one that models Dravet syndrome (DS) and another that models genetic (generalized) epilepsy with febrile seizures plus (GEFS+).
Yogendrasinh H Raol et al.
Annals of neurology, 65(3), 326-336 (2009-04-01)
Neonatal seizures occur frequently, are often refractory to anticonvulsants, and are associated with considerable morbidity and mortality. Genetic and electrophysiological evidence indicates that KCNQ voltage-gated potassium channels are critical regulators of neonatal brain excitability. This study tests the hypothesis that
Li-Li Li et al.
Frontiers in neurology, 9, 802-802 (2018-10-16)
The role of leptin in the pathogenesis of epilepsy is getting more and more attention in clinical and basic research. Although there are data indicating neuroprotective effects of elevated serum/brain leptin levels following acute seizures, no study to date has
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