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286656

Sigma-Aldrich

α-Methyl-DL-phenylalanine

98%

Synonym(s):

(±)-2-Amino-2-methyl-3-phenylpropionic acid

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About This Item

Linear Formula:
C6H5CH2C(CH3)(NH2)CO2H
CAS Number:
1132-26-9
Molecular Weight:
179.22
Beilstein:
2803960
MDL number:
MFCD00010512
UNSPSC Code:
12352209
PubChem Substance ID:
24857247
NACRES:
NA.22

Assay

98%

reaction suitability

reaction type: solution phase peptide synthesis

mp

293-294 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(N)(Cc1ccccc1)C(O)=O

InChI

1S/C10H13NO2/c1-10(11,9(12)13)7-8-5-3-2-4-6-8/h2-6H,7,11H2,1H3,(H,12,13)

InChI key

HYOWVAAEQCNGLE-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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R C Johnson et al.
Neurochemical research, 9(4), 517-528 (1984-04-01)
We studied DNA metabolism (synthesis and degradation) in brain to investigate the effect of hyperphenylalaninemia induced in rats by treatment with PCPA or alpha MPA plus PHE during suckling (4th-20th days of postnatal age) on cell proliferation and naturally occurring
B F Nore et al.
Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 48(7), 578-581 (1994-07-01)
Cyanobacterial pilin was extracted from Synechococcus 6301 membranes using a detergent mixture comprising 1% Triton X-100, 1% Thesit and 0.5% dodecyl beta-D-maltoside. Partial purification of pilin from the crude extract was achieved by a single-step purification applying the Rotofor isoelectric
M A Rubin et al.
Journal of inherited metabolic disease, 15(2), 252-260 (1992-01-01)
Wistar rats from the same litter were randomly divided into four groups and received subcutaneously from the 6th to 28th day post partum one of the following drugs: L-proline, methylmalonate, L-phenylalanine plus alpha-methylphenylalanine, or equivalent volumes of 0.9% (w/v) saline
O Greengard et al.
Biochemical pharmacology, 36(6), 965-970 (1987-03-15)
Severe hyperphenylalaninemia induced in infant rats by 3 days of treatment with p-chlorophenylalanine (p-cl phe) plus phenylalanine (phe) did not lower the tryptophan concentration of the brain, and the cerebral serotonin (5-HT) deficiency was attributable entirely to the known suppression
Yoshiyasu Ichikawa et al.
Bioscience, biotechnology, and biochemistry, 69(5), 939-943 (2005-05-26)
The stereochemistry and efficiency of an allyl cyanate-to-isocyanate rearrangement for the construction of quaternary stereocenter with nitrogen substituent was investigated by the synthesis of (R)-alpha-methylphenylalanine. The rearrangement was found to be stereospecific, and the chirality of allyl carbamate was transferred
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