Skip to Content
Merck

VEGFA

vascular endothelial growth factor A

Synonyms:
MVCD1, VEGF, VPF
Species:
UniProtKB ID:
Gene ID:
  • Human(7422) Summary: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(22339) vascular endothelial growth factor A
  • Rat(83785) vascular endothelial growth factor A
  • chicken(395909) vascular endothelial growth factor A
  • dog(403802) vascular endothelial growth factor A
  • domestic cat(493845) vascular endothelial growth factor A
  • Horse(100033839) vascular endothelial growth factor A
  • cow(281572) vascular endothelial growth factor A
  • Goat(100860957) vascular endothelial growth factor A
  • sheep(443103) vascular endothelial growth factor A
  • domestic guinea pig(100462897) vascular endothelial growth factor A
  • domestic guinea pig(100713483) vascular endothelial growth factor A
  • naked mole-rat(101702403) vascular endothelial growth factor A
  • Domestic Rabbit(100008899) vascular endothelial growth factor A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Ovine VEGF-A ELISA, for serum, plasma and cell culture supernatants,
Species
sheep
Rat VEGF ELISA Kit, for cell and tissue lysates,
Species
rat
Mouse VEGF ELISA Kit, for cell and tissue lysates,
Species
mouse
Mouse VEGF ELISA Kit, for serum, plasma, cell culture supernatant,
Species
mouse
Human VEGF ELISA Kit, for cell and tissue lysates,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-VEGF Antibody, clone JH, clone JH, Upstate®, from mouse,
Species Reactivity
human, mouse, rabbit, rat
Application
immunohistochemistry
Anti-VEGF Antibody, Alexa Fluor 488 Conjugate, from rabbit, ALEXA FLUOR 488,
Species Reactivity
human, nonhuman primates, rat
Application
immunocytochemistry
Anti-VEGF Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, primate, rat
Application
immunohistochemistry
western blot
Anti-VEGF 165b Antibody, clone 56/1, clone 56/1, 1 mg/mL, from mouse,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-VEGF Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Tranilast, ≥98% (HPLC), powder,
Species
human

Proteins

Product Number
Description
Species
VEGF121, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Species
human
SILuProt VEGFA Vascular endothelial growth factor A human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled,
Species
human
VEGF human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Vascular Endothelial Growth Factor human, VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture,
Species
human
Vascular Endothelial Growth Factor from mouse, VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture,
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human VEGFA,
Species
human
MISSION® esiRNA, targeting mouse Vegfa,
Species
mouse