U9382

Ubiquitin-Carrier Protein H10 human

≥95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution

• Synonym(s): UbcH10
• MDL number: MFCD03458906
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: human
• Quality Level: 200
• recombinant: expressed in E. coli (histidine-tagged)
• Assay: ≥95% (SDS-PAGE)
• form: buffered aqueous glycerol solution
• mol wt: ~20 kDa
• technique(s): ligand binding assay: suitable
• UniProt accession no.: O00762
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... UBE2C(11065)

Description

General description

Manufactured for Sigma by Boston Biochem., Inc.

Application

Ubiquitin-Carrier Protein H10 (UbcH10) human may be used to study the role of ubiquitin-proteasome system in pathogenesis of human diseases.

Biochem/physiol Actions

In conjunction with anaphase-promoting complex, catalyzes both cyclin A and cyclin B destruction.

In conjunction with the anaphase-promoting complex, the protein catalyzes the destruction of both cyclin A and cyclin B.

Ubiquitin-Carrier Protein H10 human also referred to as UbcH10 is a recombinant protein that catalyzes the destruction of cyclin A as well as cyclin B along with the anaphase promoting complex and hence plays a pivotal role in controlling the cell exit from mitosis.

Physical form

Solution in 50 mM HEPES, pH 8.0, 125 mM NaCl, and 1 mM DTT in 10% glycerol.

Safety Information

• WGK: WGK 1