SML1384

BEC hydrochloride

≥98% (HPLC)

• Synonym(s): S-(2-Boronoethyl)-L-cysteine, S-(2-Boronoethyl)-L-cysteine hydrochloride
• Empirical Formula (Hill Notation): C₅H₁₂BNO₄S · xHCl
• CAS Number: 63107-40-4
• Molecular Weight: 193.03 (free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825832

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: −20°C
• SMILES string: OB(O)CCSC[C@H](N)C(O)=O.C
• InChI: 1S/C5H12BNO4S.CH4/c7-4(5(8)9)3-12-2-1-6(10)11;/h4,10-11H,1-3,7H2,(H,8,9);1H4/t4-;/m0./s1
• InChI key: IMYJQAMXIIYUIH-WCCKRBBISA-N

Description

Biochem/physiol Actions

BEC (S-(2-boronoethyl)-l-cysteine) is a potent and specific arginase inhibitor that restores flow-induced responses in arterioles from diabetic rats.

BEC is a boronic analog of L-arginine, and L-cysteine. It competitively inhibits both arginase I and II. BEC does not directly affect nitric oxide synthase.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable