SAB4500989

Anti-FOLR1 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): FR-α, Folate receptor, Folate receptor α, Folate receptor 1, adult
• MDL number: MFCD02262889
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 29 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; western blot: 1:500-1:1000
• NCBI accession no.: P15328
• UniProt accession no.: P15328
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... FOLR1(2348)

Description

General description

The folate receptor 1 (FOLR1) gene encodes for folate receptor α protein, a membrane-bound glycoprotein. The FOLR1 gene is mapped on the human chromosome at 11q13.4. Anti-FOLR1 antibody detects endogenous levels of total FOLR1 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human FOLR1.

Immunogen Range: 41-90

Biochem/physiol Actions

Folate receptor α protein binds and facilitates the transport of folate into the cells. This protein acts as a therapeutic target as well as a prognostic marker for various kinds of cancers. Upregulation of the FOLR1 gene is associated with ovarian, lung, breast, brain, colorectal, and gastric cancers.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable