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L4395

Sigma-Aldrich

Liposome Kit: Lipid mixtures for the preparation of liposomes

lyophilized powder

Synonym(s):

cholesterol, L-α-phosphatidylcholine and stearylamine kit

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About This Item

EC Number:
204-695-3
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

egg yolk

Quality Level

200

form

lyophilized powder

composition

Cholesterol, 9 μmol/package
L-α-Phosphatidylcholine (egg yolk), 63 μmol/package
Stearylamine, 18 μmol/package

functional group

carboxylic acid

shipped in

ambient

storage temp.

−20°C

Application

Liposome Kit has been used for the preparation of liposomes.

Biochem/physiol Actions

Liposome Kit: Lipid mixtures for the preparation of liposomes contains cholesterol; L-α-phosphatidylcholine and stearylamine. Liposome kit may be used to prepare cationic (positively charge) liposomes for incorporation of materials into cells.
Liposomes can be used for different applications such as drug delivery, diagnostics, membrane models, adjuvants for vaccination and others. This lipid mixture can be used to encapsulate a broad spectrum of hydrophilic and amphipathic molecules of low, medium, and high molecular weight (including peptides, proteins, and oligo- and polynucleotides).

Pictograms

CorrosionEnvironment
GHS05,GHS09

Signal Word

Danger

Hazard Statements

H318 - H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Quantification of small extracellular vesicles by size exclusion chromatography with fluorescence detection
Xu R, et al.
Analytical Chemistry, 88(21), 10390-10394 (2016)
Sub-Micrometric Liposomes as Drug Delivery Systems in the Treatment and Periodontitis
Di Turi G, et al.
International Journal of Immunopathology and Pharmacology, 25(3), 657-670 (2012)
G T Köse et al.
Drug delivery, 5(4), 257-264 (1998-01-01)
Multilamellar vesicles (MLV) containing phosphatidyl choline (PC), cholesterol (CHOL), and stearylamine (SA) in the molar ratio of 7:2:0.2 were prepared by the thin film hydration method. Low-molecular-weight heparin (LMWH, MW: 3000) was conjugated with the MLV using carbodiimide (EDC). Infrared
Xuan T A Nguyen et al.
Molecular neurobiology, 56(9), 6121-6133 (2019-02-08)
The cellular prion protein (PrPC), mainly known for its role in neurodegenerative diseases, is involved in several physiological processes including neuritogenesis. In addition, its ability to bind copper or zinc has been suggested for its role in metal homeostasis. Although
Inhibition of cationic liposomes of [3H]thymidine incorporation into DNA of L1210 cells.
Laurent G, Laduron C, Ruysschaert JM, et al.
Research Communications in Molecular Pathology and Pharmacology, 31, 515-527 (1981)
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