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Key Documents

A9754

Sigma-Aldrich

2-Amino-2-methyl-1,3-propanediol

≥99%

Synonym(s):

AMPD, Ammediol

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About This Item

Linear Formula:
(HOCH2)2C(NH2)CH3
CAS Number:
Molecular Weight:
105.14
Beilstein:
635708
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

vapor density

3.63 (vs air)

vapor pressure

~10 mmHg ( 152 °C)

Assay

≥99%

form

crystalline

pH

10.5-11.5 (25 °C, 105.1 g/L)

useful pH range

7.8-9.7

pKa (25 °C)

8.8

bp

151 °C/10 mmHg (lit.)

mp

100-110 °C (lit.)

solubility

H2O: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow

application(s)

diagnostic assay manufacturing

SMILES string

CC(N)(CO)CO

InChI

1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3

InChI key

UXFQFBNBSPQBJW-UHFFFAOYSA-N

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Application

Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Used as a spacer in isotachophoresis of proteins. Also used as a buffer for the determination of alkaline phosphatase activity.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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The inhibitory effect of inorganic phosphate on the activity determination of isoenzymes of alkaline phosphatase (AP) in diethanolamine (DEA), glycine and 2-amino-2-methyl-1,3-propandiol (AMPD) buffer was studied. This effect depends on the buffer used and isoenzyme investigated. Especially the placental isoenzyme
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The isotachophoretic behavior of a model protein, serum albumin, was examined (i) by computer simulation, (ii) by capillary isotachophoresis in HPE 100 and Tachophor 2127, (iii) by continuous flow isotachophoresis in Elphor VaP 22 and the BIO-STREAM Separator and (iv)

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