Skip to Content
Merck
All Photos(1)

Key Documents

00010402

OX-23 hybridoma cell line

Anti- Factor H, human

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352200

biological source

Mouse x Mouse Hybridoma

Quality Level

ImmunoDon

BALB/c mouse spleen

Myeloma

NS0

Reactivity

Anti-Factor H, human

technique(s)

cell culture | mammalian: suitable

isotype

IgG1

shipped in

dry ice

storage temp.

−196°C

Cell Line Origin

Mouse x Mouse hybridoma

Cell Line Description

The hybridoma line OX-23 was raised by immunizing BALB/c mice with Factor H and fusion of spleen cells with NS0 mouse myeloma cells. The antibody was shown to detect human complement control protein, Factor H. OX-23, also known as MRC OX-23, reduced the increase in cofactor activity observed in the presence of OX-24 (Sigma Catalogue no. 00010403). It was reported that OX-23 and OX-24 react with different epitopes on the Factor H molecule.

Immunogen

Human Factor H

Subculture Routine

Maintain cultures between 3-9 x 100,000 cells/ml; 5% CO2; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

Disclaimer

This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Daniel Ajona et al.
Cancer research, 64(17), 6310-6318 (2004-09-03)
The complement system is important in immunosurveillance against tumors. However, malignant cells are usually resistant to complement-mediated lysis. In this study, we examine the expression of factor H, an inhibitor of complement activation, and factor H-like protein 1 (FHL-1), its

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service