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Y0001220

Captopril impurity C

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(2RS)-2-Methyl-3-sulphanylpropanoic acid, 3-Mercaptoisobutyric acid

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About This Item

Empirical Formula (Hill Notation):
C4H8O2S
CAS Number:
26473-47-2
Molecular Weight:
120.17
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

captopril

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C4H8O2S.Na/c1-3(2-7)4(5)6;/h3,7H,2H2,1H3,(H,5,6);/q;+1/p-1

InChI key

FOTPRJUNQGWLCM-UHFFFAOYSA-M

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Captopril impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H290,H301,H314,H332

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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T C Tallant et al.
Journal of bacteriology, 179(22), 6902-6911 (1997-11-26)
During growth on acetate, Methanosarcina barkeri expresses catabolic enzymes for other methanogenic substrates such as monomethylamine. The range of substrates used by cells grown on acetate was further explored, and it was found that cells grown on acetate also converted
Determination of enantiomeric purity of 3-mercapto-2-methylpropionic acid.
D Wang-Iverson et al.
Journal of chromatography, 408, 365-371 (1987-11-06)
H G Brittain et al.
Pharmaceutical research, 7(10), 1082-1085 (1990-10-01)
The ultraviolet and circular dichroism spectra of authentic captopril have been obtained, since the reported literature data are inconsistent with those obtained on highly purified material. The UV absorption spectrum consists of a single band maximum at 200 nm, while
M R Smith et al.
Bioorganic & medicinal chemistry, 2(7), 589-593 (1994-07-01)
A bacterium (strain photoB) photoassimilated 3-mercapto-2-methylpropionate as sole source of sulphur with methacrylate accumulating in the medium. This was thought to be the product of a sulphur-lyase type enzyme attacking the 3-mercapto-2-methylpropionate. Detailed examination of the biochemistry of the utilization
Erinn C Howard et al.
Science (New York, N.Y.), 314(5799), 649-652 (2006-10-28)
Flux of dimethylsulfide (DMS) from ocean surface waters is the predominant natural source of sulfur to the atmosphere and influences climate by aerosol formation. Marine bacterioplankton regulate sulfur flux by converting the precursor dimethylsulfoniopropionate (DMSP) either to DMS or to

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