S7007

Sulfadimethoxine

98.0-102.0%

• Synonym(s): 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
• Empirical Formula (Hill Notation): C₁₂H₁₄N₄O₄S
• CAS Number: 122-11-2
• Molecular Weight: 310.33
• Beilstein: 306856
• EC Number: 204-523-7
• MDL number: MFCD00057345
• UNSPSC Code: 41116107
• PubChem Substance ID: 329824574
• NACRES: NA.24

Properties

• Quality Level: 200
• Assay: 98.0-102.0%
• form: powder
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• Mode of action: DNA synthesis | interferes; enzyme | inhibits
• storage temp.: 2-8°C
• SMILES string: COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
• InChI: 1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
• InChI key: ZZORFUFYDOWNEF-UHFFFAOYSA-N

Description

General description

Chemical structure: sulfonamide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves