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428017

Sigma-Aldrich

Anti-Lamp1 Mouse mAb (LY1C6)

liquid, clone LY1C6, Calbiochem®

Synonym(s):

Anti-Lysosome-Associated Membrane Protein 1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

LY1C6, monoclonal

form

liquid

contains

≤0.09% sodium azide as preservative

species reactivity

rat

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

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L0419L1418L0668
Anti-Lamp1 Mouse mAb (LY1C6) liquid, clone LY1C6, Calbiochem®

428017

Anti-Lamp1 Mouse mAb (LY1C6)

Anti-LAMP1−Cy3™ antibody produced in rabbit 1-2 mg/mL, affinity isolated antibody, buffered aqueous solution

L0419

Anti-LAMP1−Cy3™ antibody produced in rabbit

Anti-LAMP1 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

L1418

Anti-LAMP1 antibody produced in rabbit

Anti-LAMP2 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

L0668

Anti-LAMP2 antibody produced in rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

rat

species reactivity

mouse, human, rat

species reactivity

rat, mouse, human

species reactivity

human (predicted), mouse, rat

antibody form

purified antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Gene Information

rat ... Lamp1(25328)

Gene Information

human ... LAMP1(3916)
mouse ... Lamp1(16783)
rat ... Lamp1(25328)

Gene Information

human ... LAMP1(3916)
mouse ... Lamp1(16783)
rat ... Lamp1(25328)

Gene Information

human ... LAMP2(3920)
mouse ... Lamp2(16784)
rat ... Lamp2(24944)

form

liquid

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

General description

Protein G purified mouse monoclonal antibody. Recognizes the ~120 kDa Lamp1 protein.
Recognizes the ~120 kDa Lamp1 protein.
This Anti-Lamp1 Mouse mAb (LY1C6) is validated for use in Immunoblotting, Immunocytochemistry, Immunofluorescence, Immunoprecipitation for the detection of Lamp1.

Immunogen

Rat
rat liver lysosomal membranes

Application

Immunoblotting (1 µg/ml, chemiluminescence)

Immunocytochemistry (1:100)

Immunofluorescence (see comments)

Immunoprecipitation (see comments)

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS containing 50% glycerol, pH 7.2.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

Positive Control
CHO-K1 cells

Other Notes

Kannan, K. et al. 1996. Cell Immunol.171, 10.
Rohrer, J., et al. 1996. J. Cell Biol. 132, 565.
Howe et al. 1988. PNAS85, 7577.
Lewis et al. 1985. J. Cell Biol.100, 1839.
This antibody has also been reported to work for immunofluorescence and immunoprecipitation. Antibody should be titrated for optimal results in individual systems.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Arvind Chhabra et al.
    European journal of immunology, 34(10), 2824-2833 (2004-09-16)
    Dendritic cells (DC) capture antigens from apoptotic and/or necrotic tumor cells and cross-present them to T cells, and various ways of delivering tumor antigens to DC in vitro and in vivo are being pursued. Since fusions of antigenic proteins with
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    The American journal of pathology, 175(5), 1962-1974 (2009-10-10)
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    The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(47), 12199-12211 (2008-11-21)
    In brain, monomeric immunoglobin G (IgG) is regarded as quiescent and only poised to initiate potentially injurious inflammatory reactions via immune complex formation associated with phagocytosis and tumor necrosis factor alpha (TNF-alpha) production in response to disease. Using rat hippocampal
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    Annals of neurology, 66(3), 378-389 (2009-06-25)
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    Autophagy, 10(5), 846-860 (2014-03-29)
    Neuronal autophagy is increased in numerous excitotoxic conditions including neonatal cerebral hypoxia-ischemia (HI). However, the role of this HI-induced autophagy remains unclear. To clarify this role we established an in vitro model of excitotoxicity combining kainate treatment (Ka, 30 µM)

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