700034P

7α-hydroxycholesterol

Avanti Polar Lipids

• Synonym(s): cholest-5-ene-3b,7a-diol; 110808
• Empirical Formula (Hill Notation): C₂₇H₄₆O₂
• CAS Number: 566-26-7
• Molecular Weight: 402.65
• UNSPSC Code: 12352211

Properties

• description: cholest-5-en-3β,7α-diol
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (700034P-10mg); pkg of 1 × 5 mg (700034P-5mg); pkg of 1 × 50 mg (700034P-50mg)
• manufacturer/tradename: Avanti Polar Lipids
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1
• InChI key: OYXZMSRRJOYLLO-RVOWOUOISA-N

Description

General description

7a-hydroxy-cholesterol is a B-ring substituted oxysterol.

Application

• Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.: This research investigated the relationship between bile acid metabolism and dementia through a comprehensive approach integrating metabolomics, transcriptomics, and pharmacoepidemiology. The findings suggest that alterations in bile acid synthesis may be linked to the pathogenesis of dementia (Varma et al., 2021).

Packaging

5 mL Amber Glass Screw Cap Vial (700034P-10mg)

5 mL Amber Glass Screw Cap Vial (700034P-50mg)

5 mL Amber Glass Screw Cap Vial (700034P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable