640001P
Avanti
Ceramide Delivery System
Avanti Polar Lipids
Synonym(s):
Ceramide Delivery System, Kit for C6 Ceramide Delivery
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About This Item
UNSPSC Code:
12352211
Recommended Products
Assay
>99%
form
powder
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−20°C
General description
Ceramide forms stable, fluid bilayers with cholesteryl phosphocholine, and this formulation has been shown to be more potent than solvent-delivered (DMSO) formulations of C6 Ceramide in inhibiting proliferation, inducing apoptosis, and disturbing calcium homeostasis. It is thought that DMSO formulations of C6 Cer are likely to precipitate into the cell culture medium, where the bioavailability of “crystalline” ceramide is limited. However, the formation of fluid bilayers, which are enriched in C6 Cer, prevent crystallization and allow for the transfer of monomeric ceramide to cell membranes with enhanced bioavailability.
Packaging
The kit contains 10 mg of C6 Ceramide and 13.8 mg of Cholesteryl Phosphocholine, individually packaged and ready for use.
Other Notes
Note: This delivery system works primarily with short-chain ceramides. Delivery of long-chain ceramides, e.g., C16 Cer, was generally low or absent during similar incubation times.
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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