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726176

Sigma-Aldrich

Methoxypolyethylene glycol azide

PEG average Mn 20,000

Synonym(s):

Polyethylene glycol, α-Methoxy-ω-azido-PEG, O-(2-Azidoethyl)-O′-methylpolyethylene glycol, PEG-Azide, mPEG Azide

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About This Item

Linear Formula:
N3CH2CH2(OCH2CH2)nOCH3
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.22

form

lumps

mol wt

PEG average Mn 20,000

Ω-end

azide

α-end

methoxy

storage temp.

−20°C

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Articles

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

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Kanjiro Miyata (The University of Tokyo, Japan) provides insights on the rational design of polymeric materials for “smart” oligonucleotide delivery.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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