540048

(R)-(+)-Propylene oxide

99%

• Synonym(s): (R)-(+)-1,2-Epoxypropane, (R)-(+)-Methyloxirane
• Empirical Formula (Hill Notation): C₃H₆O
• CAS Number: 15448-47-2
• Molecular Weight: 58.08
• Beilstein: 79764
• MDL number: MFCD00066211
• UNSPSC Code: 12352005
• PubChem Substance ID: 24878434
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• optical activity: [α]20/D +14°, neat
• refractive index: n20/D 1.366 (lit.)
• bp: 33-34 °C (lit.)
• density: 0.829 g/mL at 20 °C (lit.)
• functional group: ether
• SMILES string: C[C@@H]1CO1
• InChI: 1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3/t3-/m1/s1
• InChI key: GOOHAUXETOMSMM-GSVOUGTGSA-N

Description

Application

(R)-(+)-Propylene oxide is commonly employed as a chiral building block or intermediate in the synthesis of chiral compounds. For example, it can be used to synthesize cyclic propylene carbonate by the reaction with CO₂ in the presence of a chiral catalyst. It is also used as a starting material for the preparation of magnetic resonance (MR) contrast agents that can be used for in vivo detection of β-galactosidase.

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H224,H302,H311 + H331,H315,H319,H335,H340,H350
• Precautionary Statements: P210 - P233 - P280 - P303 + P361 + P353 - P308 + P313 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 1 - Muta. 1B - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): -40.0 °F - Pensky-Martens closed cup
• Flash Point(C): -40 °C - Pensky-Martens closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves