477516

N-Boc-2,5-dihydro-1H-pyrrole

96%

• Synonym(s): tert-Butyl 2,5-dihydro-1H-pyrrole-1-carboxylate
• Empirical Formula (Hill Notation): C₉H₁₅NO₂
• CAS Number: 73286-70-1
• Molecular Weight: 169.22
• MDL number: MFCD01863512
• UNSPSC Code: 12352100
• PubChem Substance ID: 24871381
• NACRES: NA.22

Properties

• Assay: 96%
• refractive index: n20/D 1.458 (lit.)
• bp: 208 °C (lit.)
• density: 0.981 g/mL at 25 °C (lit.)
• SMILES string: CC(C)(C)OC(=O)N1CC=CC1
• InChI: 1S/C9H15NO2/c1-9(2,3)12-8(11)10-6-4-5-7-10/h4-5H,6-7H2,1-3H3
• InChI key: YEBDZDMYLQHGGZ-UHFFFAOYSA-N

Description

General description

N-Boc-2,5-dihydro-1H-pyrrole, also known as tert-butyl 2,5-dihydro-1H-pyrrole-1-carboxylate, can be synthesized from N-boc-diallylamine.

Application

N-Boc-2,5-dihydro-1H-pyrrole (tert-Butyl 2,5-dihydro-1H-pyrrole-1-carboxylate) may be used in the preparation of tert-butyl 3-aryl-2,3-dihydro-1H-pyrrole-1-carboxylate.

Used in a synthesis of ß-aryl-GABA analogues by Heck arylation with arenediazonium salts.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 178.0 °F
• Flash Point(C): 81.1 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves