367532

5-Chloro-1-methyl-4-nitroimidazole

98%

• Empirical Formula (Hill Notation): C₄H₄ClN₃O₂
• CAS Number: 4897-25-0
• Molecular Weight: 161.55
• EC Number: 225-521-2
• MDL number: MFCD00233664
• UNSPSC Code: 12352100
• PubChem Substance ID: 24862766
• NACRES: NA.22

Properties

• Assay: 98%
• mp: 148-150 °C (lit.)
• SMILES string: Cn1cnc(c1Cl)[N+]([O-])=O
• InChI: 1S/C4H4ClN3O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,1H3
• InChI key: OSJUNMSWBBOTQU-UHFFFAOYSA-N

Description

General description

5-Chloro-1-methyl-4-nitroimidazole is an 4-nitroimidazole derivative.

Application

5-Chloro-1-methyl-4-nitroimidazole (CMNI) is suitable for use in the rapid mix experiments to investigate the mechanism of anomalous radiosensitization of mammalian cells by CMNI. It may be used in the synthesis of 5-aryl-1-methyl-4-nitroimidazoles, via Suzuki coupling with arylboronic acids, catalyzed by dichlorobis-(triphenylphosphine)palladium(II), K₂CO₃ and tetrabutylammonium bromide.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves