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286427

Sigma-Aldrich

L-Leucinamide hydrochloride

99%

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CONH2·HCl
CAS Number:
10466-61-2
Molecular Weight:
166.65
Beilstein:
4237021
EC Number:
233-952-2
MDL number:
MFCD00013012
UNSPSC Code:
12352209
PubChem Substance ID:
24857241
NACRES:
NA.22

Quality Level

200

Assay

99%

optical activity

[α]25/D +10°, c = 5 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

254-256 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.CC(C)C[C@H](N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1

InChI key

VSPSRRBIXFUMOU-JEDNCBNOSA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Claudio Jösch et al.
Biological chemistry, 384(2), 213-218 (2003-04-05)
Cysteinylglycine hydrolysis is a step in the metabolism of glutathione and glutathione S-conjugates. We had previously observed that in rat liver the enzymatic activity is predominantly located in the cytosol. Here we demonstrate that cytosolic leucyl aminopeptidase (EC 3.4.11.1) is
Measurement of carprofen enantiomer concentrations in plasma and urine using L-leucinamide as the chiral coupling component.
H Spahn et al.
Journal of chromatography, 433, 331-338 (1988-12-09)
HTS, chemical hybridization, and drug design identify a chemically unique antituberculosis agent-coupling serendipity and rational approaches to drug discovery.
Jialin Mao et al.
ChemMedChem, 2(6), 811-813 (2007-04-25)
B R Madan et al.
Research communications in chemical pathology and pharmacology, 58(3), 393-396 (1987-12-01)
L-leucinamide hydrochloride, an amino acid derivative, was found to share the ability of phenylbutazone in attenuating the phlogistic response induced by intraplantar injection of formaldehyde and nystatin in the unanesthetized rat. In the granuloma pouch induced by the injection of
E A Permiakov et al.
Bioorganicheskaia khimiia, 28(1), 11-15 (2002-03-06)
The kinetics of the reaction of Boc-Xaa fluorophenyl esters (where Xaa = Ala, Val, Phe, Ser, Leu, Gly, Met, Pro, or Ile) with leucinamide was studied measuring changes in the fluorescence emission at 375 nm of the fluorophenyl chromophore accompanying
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