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HPLC Analysis of CYP3A Inhibitors on Ascentis® Express RP-Amide

HPLC Analysis of CYP3A Inhibitors on Ascentis® Express RP-Amide application for HPLC

Materials

분석 컬럼

제품 번호
설명
가격

53913-U

Ascentis® Express RP-Amide, 2.7 μm HPLC Column

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

이동상 성분

제품 번호
설명
가격

70221

Ammonium formate

eluent additive for LC-MS, LiChropur™, ≥99.0%

표준 물질

제품 번호
설명
가격

N5536

Nefazodone hydrochloride

≥98% (HPLC), solid

S6319

Sertraline hydrochloride

≥98% (HPLC)

1279804

Fluoxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

1285909

Fluvoxamine maleate

United States Pharmacopeia (USP) Reference Standard

PHR1285

Lovastatin

Pharmaceutical Secondary Standard; Certified Reference Material

CONDITIONS

column

Ascentis Express RP-Amide, 10 cm x 2.1 mm I.D., 2.7 μm particles (53913-U)

mobile phase

[A] 20 mM ammonium formate in 50:50 (v/v) water:acetonitrile

flow rate

0.6 mL/min

column temp.

35 °C

detector

ESI(+), m/z 100-600

injection

1 μL

설명

분석 메모

This application demonstrates the suitability of the Ascentis Express RP Amide for the analysis of CYP3A Inhibitors.

법적 정보

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

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