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Merck

Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome.

Neuron (2017-08-05)
Sophie R Thomson, Sang S Seo, Stephanie A Barnes, Susana R Louros, Melania Muscas, Owen Dando, Caoimhe Kirby, David J A Wyllie, Giles E Hardingham, Peter C Kind, Emily K Osterweil
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Excessive mRNA translation downstream of group I metabotropic glutamate receptors (mGlu

MATERIALS
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Sigma-Aldrich
Anti-Muscarinic Acetylcholine Receptor (M1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder
Sigma-Aldrich
Forskolin, from Coleus forskohlii, โ‰ฅ98% (HPLC), powder
Sigma-Aldrich
3-Isobutyl-1-methylxanthine, ≥99% (HPLC), powder
Sigma-Aldrich
(S)-3,5-Dihydroxyphenylglycine hydrate, โ‰ฅ98% (HPLC), powder