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Merck

3D Cell Culture

Cells naturally grow and differentiate in 3D environments. Improved 3D cell culture models can more accurately replicate the native tissue environment to provide meaningful scientific conclusions. We offer a broad portfolio of solutions for 3D cell culture including products for supporting spheroid growth, scaffolds, hydrogels, organoids, ULA plates, and other cultureware.  

Close-up photo of a transparent, gel-like substance neatly contained within a circular glass dish held by a metal spoon, a sample of a hydrogel
Hydrogels

Cells embedded in 3D hydrogels can polarize, differentiate and have functional attributes that more closely resemble physiological tissues. Choose naturally derived hydrogels or reconstitute a hydrogel from synthetic materials to develop predictive cellular models.

Scanning electron microscope image depicting clusters of microbial cells adhering to a fibrous network, displayed in monochrome for detailed texture analysis.
Scaffolds for 3D Cell Culture

Cells grown on structural scaffolds engineered to mimic the ECM can be powerful, predictive models of physiological processes. Our wide range of advanced 3D cell culture scaffolds includes nanofiber, collagen, polystyrene, and polycaprolactone materials.

Fluorescence microscopy image showing the intricate, glowing green patterns of cells, highlighting the detailed cellular structure.
Organoids

Organoids are in vitro models that closely replicate the complex physiology of native tissues while also being accessible, reproducible, and scalable like traditional culture methods. Choose colon organoids, lung organoid culture systems, and patient-derived organoids from our biobank.

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