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Merck
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주요 문서

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1096779

USP

Casticin

United States Pharmacopeia (USP) Reference Standard

동의어(들):

3′,5-Dihydroxy-3,4′,6,7-tetramethoxyflavone, 3,4′,6,7-Tetra-O-methylquercetagetin, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one, Quercetagetin 3,4′,6,7-tetramethyl ether, Vitexicarpin

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C19H18O8
CAS Number:
479-91-4
Molecular Weight:
374.34
Beilstein:
1300392
MDL number:
MFCD00210481
UNSPSC 코드:
41116107
PubChem Substance ID:
329749248
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

casticin

제조업체/상표

USP

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

COc1ccc(cc1O)C2=C(OC)C(=O)c3c(O)c(OC)c(OC)cc3O2

InChI

1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3

InChI key

PJQLSMYMOKWUJG-UHFFFAOYSA-N

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일반 설명

Casticin is a flavonoid, widely used as an anti-inflammatory agent. It has anti-tumor properties and is considered to be a potent immunomodulatory and cytotoxic compound.

애플리케이션

It was may be used as reference standard to compare retention time and ion peaks in plant extracts during GC/MS analysis to quantify Casticin and artemetin.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

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문서 라이브러리 방문

Jia-Kun Shen et al.
Annals of hematology, 88(8), 743-752 (2009-01-14)
Casticin, a component from Vitex rotundifolia, widely used as an anti-inflammatory agent in Chinese traditional medicine, was reported to have anti-tumor activities. This study aims to examine the anti-leukemic activity of casticin on leukemia cells and its molecular mechanism. Cell
Pamela J Weathers et al.
Planta medica, 78(10), 1024-1026 (2012-06-08)
A number of flavonoids including casticin and artemetin from Artemisia annua have shown synergism with artemisinin against Plasmodium falciparum, but it is unclear if the flavonoids are also extracted into a tea infusion of the plant. Using a tea infusion
M Ahmed Mesaik et al.
Phytotherapy research : PTR, 23(11), 1516-1520 (2009-05-15)
Casticin (1), a flavonoid isolated from the aerial parts of Vitex agnus-castus, was found to be a potent immunomodulatory and cytotoxic compound. The activity was tested in vitro for chemiluminescence, chemotaxis, T-cell proliferation and cytotoxicity. Casticin (1) exhibited a significant

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